【目的】 通过研究多个医学专业学科、不同影响力国际医学期刊中基础研究文献比例的变化趋势,为我国医学期刊在精准医学时代的健康发展提供依据与参考。【方法】 依据Web of Science学科类别和JCR分区选取17个医学专业学科的68种期刊,在PubMed数据库中检索所选期刊1987─2016年间发表的所有文献,使用倍数变化分析基础研究文献比例的变化趋势,通过Wilcoxon秩和检验判断该变化是否具有统计学意义。【结果】 基础研究文献比例降低的现象确实存在,但并不具有普遍性,主要出现在JCR分区的Q1高影响力医学期刊中。【结论】 医学期刊应适应精准医学时代的发展要求,进一步促进基础研究与临床应用的交流。
[Purposes] The proportional change of basic research in international medical journals from multiple categories and with different influence is analyzed, so as to provide reference for the development of Chinese medical journals in the era of precision medicine. [Methods] Sixty-eight medical journals from seventeen categories were selected based on the Web of Science categories and journal quartile rankings in Journal Citation Reports (JCR). All publications from 1987 to 2016 of these journals were searched on PubMed. Then the fold change method was used to find the proportional change trends of basic science publications, and the Wilcoxon signed-rank test was used to determine the statistical significance. [Findings] The decline of basic science publications is confirmed, but it is only common in high impact journals from JCR Q1. [Conclusions] The medical journals should adapt to the development requirements of the era of precision medicine to improve the communication between basic research and clinical practice.