[Purposes] This paper aims to improve the ethical standards of medical journals in China, and promote the medical journals to play the correct ethical guiding role.[Methods] By using the method of literature analysis, through analyzing the significance of the medical journals'ethical review for human-involved research papers,the principles and practice paths were discussed.[Findings] As the final guarantee of scientific research ethics, the significance of medical journals to carry out the ethical review for human-involved research paperswere important, and some principles should be paid attention, such as protecting subjects'benefit, scientificalness and informed consent, et al.Severalmeasures were needed to achieve the ethical review, such as improving the subm ission instructions or notice to contributors, strict peer review, et al.[Conclusions] Carrying out the ethical review for human-involved research papers has important significance formedical journals,which should adhere to some principles.Somemeasures should be taken to achieve the standardized and orderly ethical review.
Human-involved medical paper,