[Purposes] This study aims to explore the existing obstacles and the key factors of the driving force breakthroughs of Chinese scientific journals to accelerate the driving innovation and obstacle cracking. [Methods] Starting with the content production, technology integration, market operation, and system design of journals, we analyzed the obstacles and their internal relationships, and the breakthrough paths of driving force. [Findings] Chinese scientific journals face four obstacles of mutual inhibition, such as the quantity of content production superior to the quality, passive and high-cost technology fusion, solidified thoughts of economic benefit, and mechanism drawbacks inhibiting each other. The above difficulties are urgent to break through. [Conclusions] Scientific journals should develop differential thoughts, explore the perspective of platform and users, promote social benefits and economic benefits simultaneously, reconstruct the management system, and extend the incentive mechanism. The combined driving of many dimensions is conducive to break through the proposed obstacles.